Product Description
| Cat Number | SEZ-HM10L |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human SEZ6L Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu29-Ala958. |
| Target | SEZ6L |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | SEZ6L, or seizure-related 6-like protein, is a neuronal protein implicated in various neurological conditions. It plays a role in motor coordination and anxiety-related behavior in mice, with SEZ6L-deficient mice displaying motor phenotypes and increased anxiety. Additionally, SEZ6L is involved in synaptic connectivity regulation and has been associated with bipolar disorder. It interacts with BACE1, the protease linked to Alzheimer's disease, suggesting its role in neurodegenerative processes. |
| Molecular Mass | The protein has a predicted MW of 103 kDa. Due to glycosylation, the protein migrates to 140-160 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Leu29-Ala958 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q9BYH1-1 |
| Amino Acid Sequence | Recombinant Human SEZ6L Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu29-Ala958. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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