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Human Tau K18 Protein (TAU-HEK18)

SKU: BTL-KB-P-03575 | Host: Human | Brand: Kactus Bio
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Product Description

Cat Number TAU-HEK18
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Human Tau K18 Protein is expressed from E.coli without tag.It contains Gln244-Glu372.
Target Tau K18
Host Human
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Scientific Background As a major microtubule-associated protein, tau plays an important role in promoting microtubule assembly and stabilizing microtubules. In Alzheimer's disease (AD) and other tauopathies, the abnormally hyperphosphorylated tau proteins are aggregated into paired helical filaments and accumulated in the neurons with the form of neurofibrillary tangles. An imbalanced regulation in protein kinases and protein phosphatases is the direct cause of tau hyperphosphorylation.
Molecular Mass The protein has a predicted MW of 13.68 kDa. The protein migrates to 17-20 kDa based on Bis-Tris PAGE result.
Sl Sequence Gln244-Glu372
Appearance Liquid
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System E.coli
Gene Id P10636-8
Amino Acid Sequence Recombinant Human Tau K18 Protein is expressed from E.coli without tag.It contains Gln244-Glu372.
Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Pdf View Document
Note The product is for research use only
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