Human TDGF1/Cripto Protein (TDG-HM101)
SKU: BTL-KB-P-03578 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | TDG-HM101 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human TDGF1/Cripto Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu31-Thr172. |
| Target | TDGF1/Cripto |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Scientific Background | TDGF1 (CRIPTO) is a member of the epidermal growth factor-Cripto-1/FRL-1/Cryptic (EGF/CFC) gene family and an obligate co-receptor involved in NODAL signaling, a developmental program implicated in midline, forebrain, and left-right axis development in model organisms. Cripto-1 is enriched in a subpopulation of embryonal, melanoma, prostate, and pancreatic cancer cells that possess stem-like characteristics. Therefore, Cripto-1 may play a role during developmental EMT, and it may also be involved in the reprogramming of differentiated tumor cells into cancer stem cells through the induction of an EMT program. |
| Molecular Mass | The protein has a predicted MW of 16.92 kDa. Due to glycosylation, the protein migrates to 23-30 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Leu31-Thr172 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P13385 |
| Amino Acid Sequence | Recombinant Human TDGF1/Cripto Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu31-Thr172. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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