Human TNFR1/CD120a/TNFRSF1A Protein (TNF-HM2R1)
SKU: BTL-KB-P-03695 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | TNF-HM2R1 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human TNFR1/CD120a/TNFRSF1A Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Leu30-Thr211. |
| Target | TNFR1/CD120a/TNFRSF1A |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of acute injury, selective inhibition of TNFR1 is predicted to attenuate the cell death and inflammation associated with TNF-α, while sparing or potentiating the protective effects of TNFR2 signalling. |
| Molecular Mass | The protein has a predicted MW of 48 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Leu30-Thr211 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P19438-1 |
| Amino Acid Sequence | Recombinant Human TNFR1/CD120a/TNFRSF1A Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Leu30-Thr211. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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