Biotinylated Cynomolgus TRAIL R2/DR5/TNFRSF10B Protein (Primary Amine Labeling) (TRL-CM1R2B)
SKU: BTL-KB-P-03718 |
Host: Cynomolgus |
Brand: Kactus Bio
Product Description
| Cat Number | TRL-CM1R2B |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Biotinylated Cynomolgus TRAIL R2/DR5/TNFRSF10B Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-terminus.It contains Ile58-Ser212. |
| Target | TRAIL R2/DR5/TNFRSF10B |
| Host | Cynomolgus |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. |
| Molecular Mass | The protein has a predicted MW of 18.28 kDa. Due to glycosylation, the protein migrates to 30-38 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Ile58-Ser212 |
| Appearance | Liquid |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | A0A2K5TXK0 |
| Amino Acid Sequence | Recombinant Biotinylated Cynomolgus TRAIL R2/DR5/TNFRSF10B Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-terminus.It contains Ile58-Ser212. |
| Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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