Human TRAIL R1/DR4/TNFRSF10A Protein (TRL-HM2R1)
SKU: BTL-KB-P-03720 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | TRL-HM2R1 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human TRAIL R1/DR4/TNFRSF10A Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ala24-Asn239. |
| Target | TRAIL R1/DR4/TNFRSF10A |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a wide range of cancers, while sparing normal cells. Despite its tremendous potential for cancer therapeutics, the translation of TRAIL into the clinic has been confounded by TRAIL-resistant cancer populations. |
| Molecular Mass | The protein has a predicted MW of 48.8 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Ala24-Asn239 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | O00220 |
| Amino Acid Sequence | Recombinant Human TRAIL R1/DR4/TNFRSF10A Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ala24-Asn239. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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