Product Description
| Cat Number | VNN-MM101 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Mouse VNN1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu24-Asn488. |
| Target | VNN1 |
| Host | Mouse |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Vanin-1 (VNN1) is anchored to the cellular membrane with pantetheinase activity, which hydrolyzes pantetheine to produce cysteamine. VNN1 can promote oxidative stress and the inflammatory response. Additionally, VNN1 has been confirmed to be overexpressed in cancer tissues of patients with PCAD and can be used as a blood biomarker for the discrimination of PCAD from type 2 diabetes. |
| Molecular Mass | The protein has a predicted MW of 53.14 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Leu24-Asn488 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q9Z0K8 |
| Amino Acid Sequence | Recombinant Mouse VNN1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu24-Asn488. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |

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