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Bay 55-9837

SKU: BTL-IB-P-00062 | Brand: Isca Biochemical
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Product Description

Cat Number VP-020
Category Peptide
Pack Size 1 mg
Description Selective VPAC2 agonist
Modification C-terminal amide
Purity >95% by hplc
Biomarker Target Vasoactive intestinal peptide (VIP) receptors
Sequence Three Letter Code H-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Val-Ala-Ala-Lys-Lys-Tyr-Leu-Gln-Ser-Ile-Lys-Asn-Lys-Arg-Tyr-NH2
Molecular Formula C167H270N52O46
Sl Sequence HSDAVFTDNYTRLRKQVAAKKYLQSIKNKRY-NH2
Solubility Soluble to 2 mg/ml in water
Appearance Freeze dried solid
Storage Store dry, frozen and in the dark
References Tsutsumi et al (2002) A potent and highly selective VPAC2 agonist enhances glucose-induced Ins release and glucose disposal: a potential therapy for type 2 diabetes. Diabetes 51 1453 PMID: 11978642Darsalia et al (2013)The specific VPAC2 agonist Bay 55-9837 increases neuronal damage and hemorrhagic transformation after stroke in type 2 diabetic rats. Neuropeptides 47(2) 133 PMID: 22981158Hadwen et al (2014) VPAC2 receptor agonist BAY 55-9837 increases SMN protein levels and moderates disease phenotype in severe spinal muscular atrophy mouse models. Orphanet J Rare Dis. 9 4 PMID: 24405637
Related areas
All peptides >All VIP receptor modulators >All diabetes research categories >All neuroscience research categories >All endocrinology research categories >
Note The product is for research use only
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