NanoComposix An International Leader in Nanomaterial Development & Commercialization
Founded in 2004, nanoComposix is headquartered in San Diego, CA, USA. nanoComposix was built with the mission of providing precisely engineered and highly characterized nanomaterials to a global customer base. nanoComposix is an FDA-registered developer and contract manufacturer. This helps to ensure that all products and services are of the highest quality and continue to meet customer expectations. The product portfolio contains hundreds of different variants of materials, size, shape, and surface, backed by extensive technical documentation and support. Development services are provided by a technical team with extensive expertise in nanotechnology, biology, chemistry, physics, and optics. nanoComposix produced the NIST nanosilver reference material, and its materials have been utilized in over 3000 peer-reviewed publications. All materials are supplied with certificates of analysis that include electron microscopy, hydrodynamic diameter, and optical data for each batch to guarantee products meet specifications.
BTL Biotechno Labs Pvt. Ltd. is proud to partner with nanoComposix to make a complete range of their products available in India. Our collaboration with nanoComposix allows us to provide a comprehensive suite of services, including rapid prototyping, characterization, integration, and scale-up solutions. These solutions can significantly speed up the R&D and commercialization processes for a broad range of applications, such as biodiagnostics, topical therapeutics, nanomedicine, antimicrobial coatings, and colour engineering. By combining our expertise and resources, we are bringing cutting-edge nanotechnology-enabled products to the Indian market.
nanoComposix provide services for the development and manufacturing of Lateral Flow Assays, Nanoparticles and GMP.
Lateral Flow Assay & Services:
NanoComposix is a full-service lateral flow development company specializing in the design and manufacture of ultra-sensitive quantitative diagnostic assays. Their services span all phases of the development cycle, from
feasibility to manufacturing. They also offer industry-leading technologies for increasing assay sensitivity as well as starter kits to help build and optimize your lateral flow assay.
Conjugation Kits for Lateral Flow Assay Development
Fortis Life Science offers a range of different conjugation kits that can be used to screen, optimize and build lateral flow assays. These kits feature a range of components that allow quick and easy screening of a range of different materials, saving on both time and money during research and development.
The Full Kit includes different grades of the following
- Nitrocellulose membranes
- Conjugate pads
- Sample pads, including blood separation pads
- Wick pads
- Backing cards
- Storage pouches
Gold Conjugation Kit for Lateral Flow: Gold conjugation kits are suitable for researchers looking to improve existing or develop new lateral flow assay tests. This kit contains the components necessary to pre-screen and validate critical reagents and supplies, which are crucial for success.
Gold conjugation have multiple applications in life science research, and therefore we provide the complete range of their custom services to the Indian scientific community for the development of food safety assays, kits for the detection of physiological disorder biomarkers, lateral flow assays for therapeutic drug monitoring, infectious disease detection by nucleic acid lateral flow kits, and disease-causing bacteria detection lateral flow assay kits.
NHS Dried Kits: NHS-activated conjugation kits contain the components needed to make initial conjugation sweeps easy - with no EDC / NHS activation required. These BioReady products are specially formulated for the attachment of a molecular recognition element, such as an antibody for lateral flow and bio diagnostics.
Nanomaterials for Targeted Drug Delivery & Photothermal Therapy
Since 2004, nanoComposix has provided monodisperse and unagglomerated metal and metal-oxide nanomaterials to thousands of customers. Hundreds of different variants of material, size, shape, and surface are available as stock products and we have produced over 2000 custom core/shell, biofunctionalized, fluorescent, and magnetic nanocomposites to meet client specifications.
- Gold nanoparticles are readily conjugated to antibodies and other proteins due to the affinity of sulfhydyl (-SH) groups for the gold surface, and gold-biomolecule conjugates have been widely incorporated into diagnostic applications, where their bright red color is used in home and point-of-care tests such as lateral flow assays.
- Gold nanomaterials can be conjugated to biomolecules to specifically target cancer cells and used for photothermal cancer therapy, where their tunable optical properties cause them to convert laser light into heat and selectively kill cancerous cells.
- Gold nanoparticles have unique optical properties because they support surface plasmons. At specific wavelengths of light, the surface plasmons are driven into resonance and strongly absorb or scatter incident light. This effect is so strong that it allows for individual nanoparticles as small as 30 nm in diameter to be imaged using a conventional dark field microscope.
- Spherical gold (2–200 nm) with citrate at 0.05 mg/mL
- Spherical gold (2–200 nm) with dodecanethiol and PVP dried; polystyrene, silica, aminated silica surfaces at 1 mg/mL
- Gold nanoshells (660, 800, 980 nm resonances) with PEG, PVP, carboxyl surfaces at 0.05 & 1 mg/mL
- Silver shelled gold (20, 60, 80 nm) with citrate at 1 mg/mL
- Gold nanorods (660, 800, 980 nm resonances) with citrate, PEG, PEG-carboxyl surfaces at 1 & 50 OD
Spherical gold (5–100 nm) with citrate, aminated, carboxyl, PEG, PVP surfaces at 1 mg/mL
Spherical gold (40 & 80 nm) & gold nanoshells (150 nm with citrate, carboxyl, Streptavidin surfaces at 10 & 20 OD
Spherical gold (10–100 nm) with PEG-carboxyl surface at 0.05 mg/mL
Silver nanoparticles are widely incorporated into wound dressings, and are used as an antiseptic and disinfectant in medical applications and in consumer goods. Silver nanoparticles have a high surface area per unit mass and release a continuous level of silver ions into their environment. The silver ions are bioactive and have broad-spectrum antimicrobial properties against a wide range of bacteria. By controlling the size, shape, surface, and agglomeration state of the nanoparticles, specific silver ion release profiles can be developed for a given application.
Incorporation of silver particles into plastics, composites, and adhesives increases the electrical conductivity of the material. Silver pastes and epoxies are widely utilized in the electronics industries. Silver nanoparticle-based inks are used to print flexible electronics and have the advantage that the melting point of the small silver nanoparticles in the ink is reduced by hundreds of degrees compared to bulk silver. When scintered, these silver nanoparticle-based inks have excellent conductivity.
Silver nanoparticles have unique optical properties because they support surface plasmons. At specific wavelengths of light the surface plasmons are driven into resonance and strongly absorb or scatter incident light. This effect is so strong that it allows for individual nanoparticles as small as 20 nm in diameter to be imaged using a conventional dark field microscope. This strong coupling of metal nanostructures with light is the basis for the new field of plasmonics. Applications of plasmonic silver nanoparticles include biomedical labels, sensors, and detectors. It is also the basis for analysis techniques such as Surface Enhanced Raman Spectroscopy (SERS) and Surface Enhanced Fluorescent Spectroscopy.
There is increasing interest in utilizing the large scattering and absorption cross-sections of plasmonic silver nanoparticles for solar applications. Since the nanoparticles act as efficient optical antennas, very high efficiencies can be obtained when the nanoparticles are incorporated into collectors.
- Spherical silver (4–200 nm) with citrate at 0.02 mg/mL
- Spherical silver (4–100 nm) with dodecanethiol and PVP dried; silica, aminated silica surfaces at 1 mg/mL
- Silver shelled gold (20, 60, 80 nm) with citratel at 1 mg/mL
- Silver nanoplates (660, 800, 980, 1064 nm resonances) with PVP & silica surfaces at 0.02 & 1 mg/mL
- Silver nanocubes (55, 75, 100 nm) with PVP surface at 1 mg/mL
Spherical silver (5–200 nm) with citrate, aminated, carboxyl, PEG, PVP surfaces at 1 mg/mL
Colloidal silica (silicon dioxide) nanoparticles are amorphous materials and are generally spherical in shape. They can be made to have a broad range of sizes and their surface chemistry is easily modified to target a variety of applications. Regardless of size, dried silica nanoparticles are a white powder.
In their nonporous form, silica nanoparticles are known for being absorbent and abrasive, whereas mesoporous silica nanoparticles have important applications in drug delivery and nanomedicine.
- Mesoporous Silica Nanospheres (Silica)
- Mesoporous Silica Nanospheres (Silica Dried)
- Mesoporous Silica Nanospheres (Aminated Silica)
- Mesoporous Silica Nanospheres (Aminated Silica Dried)
- Gold Nanospheres (Silica Shelled)
- Gold Nanospheres (Silica Shelled Animated)
Platinum nanoparticles are used in a variety of applications, including catalysis, Surface Enhanced Raman Spectroscopy and molecular diagnostics. Platinum nanoparticles from nanoComposix have:
- Diameters of 5, 30, 50 and 70 nm, with guaranteed CVs < 15% (CV < 20% for 5 nm spheres)
- TEM, UV-Vis, and DLS characterization data provided for every batch
- A citrate surface and are provided in a citrate buffer
Platinum Nanoparticles Bare (Citrate)
Platinum Nanoparticles Bare (Citrate)
Custom Nanoparticle Synthesis
NanoComposix has a multi-disciplinary team of scientists with backgrounds in chemistry, physics, engineering, and earth sciences. They have worked with over a hundred different clients to develop materials, composites, and formulations with tailored optical and physical properties for a wide range of applications, including medical devices, nanoparticle drug delivery, optical sensors, and consumer products. No two applications or experiments are the same; standard products can be modified or new materials developed as per the research needs.
DLS Analysis, Endotoxin Testing, ICP-MS, TEM Analysis, UV-Vis Analysis, & Zeta Potential Due to their small size, low mass, and extremely high surface area-to-volume ratios, once nanoparticles bind together, it is often impossible to separate them. Consequently, most dried gold nanopowders that are resuspended consist of clusters of hundreds of individual nanoparticles. For many plasmonics and biomedical applications, this agglomeration significantly degrades performance. To overcome these challenges, we provide custom processing techniques that allow us to concentrate and purify nanoparticles without inducing agglomeration. The particles can be transferred into a variety of different solvents to enable their integration into a wide variety of systems. In addition, we have developed a surface stabilization technique that allows us to produce dried gold nanoparticles that can be redispersed into individual, monodisperse nanoparticles.
We, BTL Biotechno Labs Pvt. Ltd., a distributor of nanocomposite, offer their complete range of products to bring nanotechnology-enabled products to market in India. For nearly 20 years, nanocomposite has provided monodisperse and unagglomerated metal and metal-oxide nanomaterials to thousands of customers for varied uses, including Lateral Flow, Drug Delivery, Plasmonics, Optical Engineering, Surface Coatings, and more. We, together with nanoComposix, provide rapid prototyping, characterization, integration, and scale-up solutions to accelerate R&D and commercialization for a wide variety of application areas, including diagnostics, topical therapeutics, nanomedicine, antimicrobial coatings, and colour engineering.
For more details, please follow the link below: