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Beta-Amyloid (1-40) Peptide

By: Team BTL Biotechno Labs Pvt. Ltd.

Amyloid beta (Aβ or Abeta) denotes peptides of 1–40 amino acids that are the main component of the amyloid plaques found in the brains of people with Alzheimer's disease (AD). The peptides derive from the amyloid-beta precursor protein (APP), which is cleaved by beta secretase and gamma secretase to yield Aβ in a cholesterol-dependent process and substrate presentation. The sequential proteolytic cleavage of the Amyloid Precursor Protein (APP) by secretases (α, b, g) generates beta-Amyloid peptide fragments, of which beta-Amyloid 1-42 forms a major component of amyloid plaques in neurons of AD brains. Beta-Amyloid 1-40 is the other major C-terminal variant of the Amyloid protein and is usually taken as a negative control when studying beta-Amyloid 1-42 effects in AD. Beta-Amyloid 1-40 is the primary soluble species with a 10-fold higher secretion than that of beta-Amyloid 42 in normal brains.

BTL Biotechno Labs - channel partner of Anaspec

We, BTL Biotechno Labs Pvt. Ltd., a channel partner of Anaspec, provide their largest collections of beta-amyloid 1-40 peptides, including native and modified sequences, and specialized formulations, featuring Aggresure™ and GMP-grade (for in vitro use), to the Indian scientific community to promote research on Alzheimer's disease.

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Biotechnolabs well known as Leading Importer and supplier of ELISA kits & Antibodies in India

Beta-amyloid 1-40 peptides | AnaSpec