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Cutting-Edge Research Tools for Sickle Cell Disease

Cutting-Edge Research Tools for Sickle Cell Disease

Sickle cell disease and its variants are the most prevalent hereditary blood disorders, impacting 100 million individuals worldwide. The term sickle cell disease includes a group of common inherited genetic disorders characterized by a point mutation in the gene encoding the beta subunit of hemoglobin (HBB). This genetic change involves a homozygous missense mutation [Glu6Val, rs334] in the beta-globin gene, which, when deoxygenated, leads to the polymerization of hemoglobin S (Hb S). This single DNA base alteration sets off a chain of physiological consequences that can affect various organs and systems. The polymerization of two mutant sickle beta-globin subunits causes red blood cells to adopt a crescent or sickle shape, hence the name sickle cell disease (SCD). SCD is a very serious disease. It can be life-threatening. It can lead to anemia (a shortage of red blood cells), causing fatigue and possibly damage to blood vessels and vital organs. There is no single best treatment for all people with SCD.
To date, the only cure for SCD is a bone marrow or stem cell transplant. At the same time bone marrow or stem cell transplants are very risky and can have serious side effects, including death.
To support research and advances in the treatment of Sickle cell disease, BTL Biotechno Labs Pvt. Ltd., as a leading supplier of life science research products, is offering a comprehensive range of research products related to Sickle cell disease including haemoglobin beta S, C, A, F, epsilon and delta antibodies, ELISA kits, ready-to-use RNA, and many others. BTL Biotechno Labs Pvt. Ltd. are committed to making these high-quality research products accessible to the Indian scientific community at competitive and affordable prices.

For more details, please contact us @ https://lnkd.in/d2FEZ8k2

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