What is compound library screening?

The term compound library refers to a collection of substances that can be employed in high-throughput screening and other drug development procedures. Chemical library databases typically preserve the properties of a chemical compound, such as its structure, purity, and quantity, for future use.

What are screening libraries?

A screening library is a collection of substances or pieces of substances that are tested against a target that has been identified as being crucial in a therapeutic field. A larger chemical space can be examined against the target of interest by screening a variety of chemicals.

How does high throughput screening work?

Data collection for high-throughput screens is typically done by an optical measurement that measures how much light the sample generated. There are various readouts available, including light scattering (turbidity), fluorescent or luminescent detection, and colourimetry.

What is used as screening of chemicals?

Target-based assays, such as enzymatic or binding-based assays using purified proteins, are typically used in high throughput chemical screening, but phenotypic assays that look at specific marker expression (by reporter or staining), protein activity, or cell behaviours in cell culture are becoming more common.

Compound Screening Library | Chemicals Supplier in india

Compound Screening Library

Drug discovery is a highly complex and multidisciplinary process which goal is to identify new drugs against various diseases. Generally, it has been observed that in current drug discovery research, one marketable drug emerges from screening of one million compounds. Compound library screening is performed by most pharmaceutical companies during the drug development process through using vast compound libraries to identify potential targets. Searching for an inhibitor that could potentially become a drug requires thousands of data points. Hence, high-throughput screening (HTS) has become essential in this process. The cost pressure in screening is enormous but the researchers have opted for miniaturization.

The most robust, high quality small molecule libraries incorporate compounds with desirable traits.These libraries are widely used in target identification, high-throughput/focused screening for new hits that might be developed into a drug, drug repositioning/repurposing, predictive toxicology, or new target discovery through the integration of small-molecule chemogenomic with genetic approaches, such as RNA-mediated interference and CRISPR/Cas9.

BTL Biotechno Labs Pvt. Ltd. has chemical compound libraries that consist of 10,000+ small molecules with validated pharmacological and biological activities. These libraries are for High throughput screening and high content screening. Various advantages of compound libraries:

These are useful tool for locating new targets for old drugs
Bioactivity and safety confirmed by clinical trials
Products are NMR and HLPC validated to ensure high purity
They have diversity in structure, medicinally active and permeable to cells
They have applications in various fields: oncology, immunology, neuropsychiatry, cardiology, analgesia, anti-inflammatory, cancer, stem cell, Neuronal Signalling, Immunity, GPCR, epigenetics etc
They include targets of more than 10 signalling pathways like: apoptosis, the PI3K/Akt/mTOR, and MAPK pathways.
Safety and effectiveness have been demonstrated by pre-clinical or clinical studies. Some of them are FDA approved. We are an authorized chemicals suppliers in Delhi, India., India with years of experience in delivering chemicals and related products.

Not only this BTL Biotechno Labs Pvt. Ltd. also has screening libraries of more than 3,000 natural products which include antioxidants, anti-inflammatory, antibacterial, anticancer etc among which some of them are FDA approved and are NMR and HPLC validated. These are a strong weapon for the cell induction research

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