Understanding the novel coronavirus and curbing the spread of COVID-19 requires a diverse array of reagents. One of the most important tools is Enzyme-Linked Immunosorbent Assays (ELISAs), qualitative and quantitative tests for the detection of different molecules. In the case of SARS-COV-2 and COVID-19, these kits detect patient immunoglobulins against viral proteins to assess immunity. Emerging evidence suggests that hyperactivity of the immune system after SARS-COV-2 infection can trigger excessive release of cytokines such as IL-6, TNF alpha and IFN gamma. This rapid immune escalation is called the cytokine storm syndrome and can lead to severe lung damage and death.

Proteintech offers well-validated and highly sensitive indirect and sandwich ELISA kits for detecting immunoglobulins against SARS-CoV-2 proteins and the cytokines involved in cytokine release syndrome. These kits are developed and validated to detect IgG and IgM immunoglobulins against Receptor Binding Domain (RBD) of SARS-CoV-2 Spike protein (S protein) and Nucleocapsid protein (N Protein). Proteintech`s wide range of cytokine-specific ELISA kits are extensively validated using in-house developed, human cell-expressed cytokines.

They can assist in figuring out whether someone has been exposed to SARS-CoV-2 and has experienced an immunological reaction. ELISA kits that were offered at the time of my knowledge cutoff are illustrated by the following:

IgG and IgA antibodies to SARS-CoV-2 can be found using ELISA assays from Euroimmun, which also sells anti-SARS-CoV-2 tests. These tools are made to deliver both qualitative and quantitative outcomes. Solgent's DiaPlexQTM SARS-CoV-2 IgG ELISA kit is intended to identify IgG antibodies that are specific to the SARS-CoV-2 spike protein. It offers a numerical outcome.

Vircell offers ELISA kits for the detection of IgG and IgM antibodies against SARS-CoV-2. Vircell COVID-19 ELISA KITS. These test kits are made for precise detection. It's crucial to remember that ELISA kits' sensitivity, specificity, and functionality can vary. It's important to take into account aspects like intended use, validation status, and regulatory approvals for diagnostic purposes when choosing a kit.