Collagen Induced Arthritis

Collagen-induced arthritis has been used as a model for inflammatory arthritis, where immunization of susceptible strains of mice with type II collagen leads to the development of arthritis with features similar to those of human inflammatory arthritis.

We, BTL Biotechno Labs Pvt. Ltd., an authorized channel partner of Chondrex in India, provide their extensive range of collagen, including species and types of highly purified type II, IX, and XI cartilage collagen for inducing Collagen-Induced Arthritis (CIA) at competitive price. CIA can be induced in rodents and non-human primates by immunization with type II collagen; it has also been reported that type XI is capable of inducing arthritis in mice and rats because the alpha 3 (XI) chain of type XI collagen is identical to the alpha 1 (II) chain of type II collagen. To effectively induce CIA in animals, the type of adjuvant used for emulsifying collagen is a key element. Therefore, we also offer their both Incomplete Freund’s Adjuvant (IFA) and Complete Freund’s Adjuvant (CFA) containing various amounts of M. tuberculosis to optimize the immunization condition for inducing CIA.Z

For more details, please follow the link below:
https://lnkd.in/d7ZQv69x

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